CHEM 5561 Principles and Methods in Biophysical Chemistry
This course is an introduction to the key principles and experimental methods of contemporary biophysics and biophysical chemistry. The course primarily discusses the structures and dynamics of biomolecules (such as nucleic acids and proteins), including the biophysical principles and measurements for biomolecular folding/unfolding, as well as determination of biomolecular structure and dynamics by methods such as X-ray crystallography, cryogenic electron microscopy, and Nuclear Magnetic Resonance spectroscopy. Critical evaluations of determined structures by selected methods and applications of structural biology will be emphasized. The course will also cover principles and methods for determining ligand binding to biological macromolecules.
Course overview
- Department
- Chemistry
- School
- MCAS
- Credits
- 3
- Level
- Both
- Offered
- Annually
Catalog details
Course evaluations
- Course rating
- 4.30 / 5 · Very Good
- Instructor rating
- 4.40 / 5 · Very Good
- Terms evaluated
- 2
| Term | Instructor | Course overall | Instructor overall | Well organized | Clear learning objectives | Intellectually challenging | Helpful assignments | Applicable beyond course | Attendance necessary | Weekly effort | Responses |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Spring 2025 | Huiqing Zhou | 4.8 | 4.7 | 4.7 | 4.7 | 4.3 | 4.8 | 4.7 | 4.8 | 1–3 hrs/week | 6 of 6 |
| Spring 2024 | Huiqing Zhou | 3.5 | 4.0 | 4.0 | 4.0 | 4.3 | 4.5 | 3.8 | 4.5 | ≤ 1 hr/week | 4 of 9 |